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12 Studies Explaining How Cannabis Stops Epileptic Seizures

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Below is a list of 12 studies showing the power cannabis has when it comes to epilepsy. Apart from all of the science that’s emerged over the years in this area, there are a number of real world examples as well. That being said,  The exact cannabinoid formula for each specific kind of epilepsy remains elusive, but the scientific evidence so far suggests that finding it is only a question of time. For parents who go through this process, it takes quite some time. Here is one of multiple examples.

 

  1. Evan C. Rosenberg, Pabitra H. Patra, and Benjamin J. Whalleyb; Therapeutic effects of cannabinoids in animal models of seizures, epilepsy, epileptogenesis, and epilepsy-related neuroprotection; May 2017; 319–327
  2. Gloss D, Vickrey B; Cannabinoids for epilepsy; March 2014
  3. Wallace MJ, Blair RE, Falenski KW, Martin BR, DeLorenzo RJ; The endogenous cannabinoid system regulates seizure frequency and duration in a model of temporal lobe epilepsy; October 2003; 129-37
  4. Rosenberg EC, Tsien RW, Whalley BJ, Devinsky O; Cannabinoids and Epilepsy; October 2015; 747-68
  5. Jones NA, Hill AJ, Smith I, Bevan SA, Williams CM, Whalley BJ, Stephens GJ; Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo; February 2010; 569-77
  6. Hill AJ, Mercier MS, Hill TD, Glyn SE, Jones NA, Yamasaki Y, Futamura T, Duncan M, Stott CG, Stephens GJ, Williams CM, Whalley BJ; Cannabidivarin is anticonvulsant in mouse and rat; December 2012; 1629-42
  7. Orrin Devinsky, Eric Marsh, Daniel Friedman, Elizabeth Thiele, Linda Laux, Joseph Sullivan, Ian Miller, Robert Flamini, Angus Wilfong, Francis Filloux, Matthew Wong, Nicole Tilton, Patricia Bruno, Judith Bluvstein, Julie Hedlund, Rebecca Kamens, Jane Maclean, Srishti Nangia, Nilika Shah Singhal, Carey A Wilson, Anup Patel, Maria Roberta Cilio; Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial; March 2016; 270–278
  8. Elizabeth A Thiele, Eric D Marsh, Jacqueline A French, Maria Mazurkiewicz-Beldzinska, Selim R Benbadis, Charuta Joshi, Paul D Lyons, Adam Taylor, Claire Roberts, Kenneth Sommerville; Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWP CARE4): a randomised, double-blind, placebo-controlled phase 3 trial; March 2018; 1085–1096
  9. Orrin Devinsky, J. Helen Cross, Linda Laux, Eric Marsh, Ian Miller, Rima Nabbout, Ingrid E. Scheffer, Elizabeth A. Thiele, Stephen Wright; Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome; May 2017
  10. Devinsky O, Cilio MR, Cross H, Fernandez-Ruiz J, French J, Hill C, Katz R, Di Marzo V, Jutras-Aswad D, Notcutt WG, Martinez-Orgado J, Robson PJ, Rohrback BG, Thiele E, Whalley B, Friedman D; Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders; June 2014; 791-802
  11. Sulak D, Saneto R, Goldstein B; The current status of artisanal cannabis for the treatment of epilepsy in the United States; May 2017; 328-333
  12. Elisabetsky E, Brum LF, Souza DO; Anticonvulsant properties of linalool in glutamate-related seizure models; May 1999; 107-13
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